Micro-organisme novateur

Willaertia magna C2c Maky

Identity card

  • Common noun

    Willaertia magna C2c Maky

  • Type


  • Species

    Willaertia magna

  • First description

    Jonckheere et al. in 1984

  • Strain

    W. magna C2c Maky (natural state)

  • Origine

    Aix-Les-Bains Thermal waters

A water-borne microorganisms


Discovered in the thermal waters of Aix-Les-Bains (France) in 1998 by Professor Pernin, this amoeba is a natural predator of water-borne microorganisms (including opportunistic pathogenic bacteria such as: Legionella, Pseudomonas, Listeria, Klebsiella, etc.).


Amoeba has demonstrated that Willaertia magna C2c Maky has a biocidal effect on more than 50 different strains to date.

Its particularity


Amoebae derive the basis of their biocidal feature from their lifestyle: they use phagocytosis to feed, a mechanism that allows cells to internalize and digest particles and microorganisms. However, there is a group of bacteria called Amoeba Resistant Bacteria (ARBs) such as legionellae, which are able to hijack the amoebas cellular machinery and use it to multiply inside their vesicles. These amoebas are then said to be permissive. The Willaertia magna C2c Maky strain behaves very differently, it is not permissive and prevents the internalized bacteria from multiplying. This property is precisely at the origin of the robustness and efficiency of its biocidal effect.


Willaertia magna C2c Maky is also able to internalize and phagocytose vectors of Legionella pneumophila, such as permissive free amoebae. Indeed, the ability of Willaertia magna C2c Maky to internalize and eliminate other free amoebae has been demonstrated both in the laboratory and under natural conditions, such as in raw industrial water.

Without danger

The absence of toxicity, pathogenicity and ecotoxicity of Willaertia magna C2c Maky allows it to be classified without hazard class (neither physical hazards, nor risks to human and animal health, nor environmental risks) according to the regulation (EC) No 1272/2008 on classification, labeling and packaging of substances and mixtures (CLP).