Dernièrement…

🏆 #Amoéba remporte l’Innovation Award
A l’occasion de la 3ème édition du #symposium @PBioprotech, les équipes d’Amoéba ont eu le plaisir de voir leur travail récompensé ! Un grand merci au jury pour avoir choisi notre #innovation #biocontrôle parmi les 11 candidats !

#Amoéba au @PBioprotech de Reims 🌱
Du 28 au 30 juin, notre directrice #scientifique Sandrine Demanèche représentera #Amoéba au Plant BioProTech à Reims, et y présentera notre #innovation #biocontrôle devant plus de 300 intervenants de la communauté #scientifique.

📣 Communiqué de Presse : https://bit.ly/3NOLUON
#Amoéba annonce l’émission de la cinquième tranche de 60 obligations convertibles en actions (#OCA) dans le cadre de son financement obligataire avec programme d’intéressement conclu avec @niceandgreen_sa.

🌧 Suite aux violents épisodes #orageux et #grêleux de ce week end de la Pentecôte dans plus de 65 #départements, #Amoéba souhaite exprimer son soutien à tous les #agriculteurs dont les cultures ont été endommagées.

Micro-organisme novateur

Production

Amoeba producer

 

Amoéba is positioned as a research and development platform for amoeba production.

 

Its know-how acquired during years of testing and trials make it an outstanding unit, always at the forefront of optimization.

Our production process is characterized by three main axes:

 

Various steps were necessary to reach the level of expertise in industrial production of the microorganism that Amoeba has today.

 

Willaertia Magna C2c Maky is not a pathogenic microorganism. This amoeba was little studied in the past and the scientific articles that mentioned it could be counted on the fingers of one hand. These publications allowed us to start our research, but later, we had to be creative to develop our know-how.

1. A suspension culture

Adhesion culture, an unsuitable process:

In its early days, Amoeba produced its amoebas on plates (cell culture flasks) in adhesion. Willaertia Magna C2c Maky developed on the surface for 2D production. This is the classical method of amoeba culture in the laboratory.

This method, although effective, was not efficient. The surface and the volume of culture medium necessary to produce the desired quantity of amoebae were important brakes towards an industrialization of the production.

 

The transition from 2D to 3D culture:

Thanks to an extensive research phase, Amoéba’s teams succeeded in developing a means to transform production from 2D to 3D culture. This resulted in considerable space savings and a remarkable improvement in productivity and output.

To produce the same quantity of amoebas, a suspension culture requires a space of 2m2, while an adhesion culture would have required 21,500m2.

 

Amoeba has successfully evolved this process towards amoeba suspension culture through numerous studies. This process has revolutionized the company’s approach to production. Months of work followed to carry out a scale up, which allows Amoéba today to be able to supply our biocide on a European scale.

2. A continuous production

 

In order to always optimize its yields, Amoéba looked for a solution that would allow it to standardize the production volume while limiting the risks of quality deterioration.

 

Continuous infusion of the culture medium:

By using a process of continuous infusion of the culture medium into the bioreactors (where the amoebas develop), Amoeba secures its production thanks to the robustness of this process. This guarantees a constant harvest at a known volume because each parameter is controlled and monitored.

3. A unique culture medium

 

To meet the needs of a continuous suspension culture, the culture medium used to provide a favourable environment for amoeba development had to be custom-made.

 

Amoeba is the sole owner of this formula with unique physico-chemical parameters.