Willaertia magna C2c Maky
Identity card
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Common noun
Willaertia magna C2c Maky
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Type
Willaertia
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Species
Willaertia magna
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First description
Jonckheere et al. in 1984
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Strain
W. magna C2c Maky (natural state)
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Origine
Aix-Les-Bains Thermal waters
A water-borne microorganisms
Discovered in the thermal waters of Aix-Les-Bains (France) in 1998 by Professor Pernin, this amoeba is a natural predator of water-borne microorganisms (including opportunistic pathogenic bacteria such as: Legionella, Pseudomonas, Listeria, Klebsiella, etc.).
Amoeba has demonstrated that Willaertia magna C2c Maky has a biocidal effect on more than 50 different strains to date.
Its particularity
Non-permissive
Amoebae derive the basis of their biocidal feature from their lifestyle: they use phagocytosis to feed, a mechanism that allows cells to internalize and digest particles and microorganisms. However, there is a group of bacteria called Amoeba Resistant Bacteria (ARBs) such as legionellae, which are able to hijack the amoebas cellular machinery and use it to multiply inside their vesicles. These amoebas are then said to be permissive. The Willaertia magna C2c Maky strain behaves very differently, it is not permissive and prevents the internalized bacteria from multiplying. This property is precisely at the origin of the robustness and efficiency of its biocidal effect.
Regulator
Willaertia magna C2c Maky is also able to internalize and phagocytose vectors of Legionella pneumophila, such as permissive free amoebae. Indeed, the ability of Willaertia magna C2c Maky to internalize and eliminate other free amoebae has been demonstrated both in the laboratory and under natural conditions, such as in raw industrial water.
Without danger
The absence of toxicity, pathogenicity and ecotoxicity of Willaertia magna C2c Maky allows it to be classified without hazard class (neither physical hazards, nor risks to human and animal health, nor environmental risks) according to the regulation (EC) No 1272/2008 on classification, labeling and packaging of substances and mixtures (CLP).